Syllabus
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Prerequisites:
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Graduate students in engineering and physical science or
senior undergraduate students
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Textbook:
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There is no textbook. The lecturing is mainly based on
the notes, selected research articles of journals, and sections from the
following references. The lecture notes and supplementary materials will be
posted on the webpage.
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References: |
1. Manz and H. Becker, Microsystem
Technology in Chemistry and Life Science
2. R. Eggins, Chemical Sensors and
Biosensors
3. T. A. Kovacs, Micromachined
Transducers Sourcebook
4. M. Mardou, Fundamentals of
Microfabrication
5. Oosterbroek
and van den Berg, Lab-on-a-chip Miniaturized Systems for (Bio)Chemical
Analysis and Synthesis
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Grading:
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Homework 40 %, Midterm exam 25 %, Labs
10%, Project presentations 10%,
Final report 10%, Class activities 5%
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Homework:
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Homework will be due one week after it has been given,
except when otherwise advised. Homework must be submitted at the beginning
of the class on the day it is due. Late submissions will be penalized 10 %
for every day it is late up to one week. After one week, homework will not
be accepted.
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HW1:
HW2:
HW3:
Midterm:
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Due: 2/18
Due: 3/29
Due: 4/26
April 14, 2016
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Labs:
Term Project:
Report
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Lab I: Microfluidics, March 29 & 31 (meet in Clark 123 at 10:30am)
Lab
I handout
Term Project Requirement
May 13
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Topics:
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Lecture notes
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Reading Material
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1. Introduction to BioMEMS
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BioMEMS
Introduction
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Lab-on-a-chip
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2. Scaling laws
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Scaling I
Scaling II
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Feynman
Scaling
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3. Microfabrication process
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Microfabrication I
Microfabrication II
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Microfabrication
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4. Polymer-based microfabrication
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Soft-Lithography
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Soft
Lithography |
5. Fluidics basics
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Fluids
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Microfluidics
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6. Microfluidic control & measurement
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Microfluidic
Control I
Microfluidic
Control II |
Microfluidics-Ho
Molecular
Manipulation |
7. Forces and fields at the microscale
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Force & Field
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Electrokinetics-I
Electrokinetics-II |
8. Lab-on-chip systems
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Lab-on-a-chip
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9. Single-Molecule detection
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10. Micro/Nano
biosensors
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