Translating Micro/Nano Engineering Innovations into Clinic

Our lab focuses on the development of new technologies for molecular analysis and biomedical research via advances in micro- and nano-scale sciences. We aim to develop new methods, devices and systems with unprecedented performance characteristics, such as sensitivity, specificity, resolution (temporal and/or spatial), multiplexing and throughput to rectify current technological limitations in the molecular study of diseases. By forging long-term collaborations with medical scientists and physicians across various disciplines (e.g. Oncology, Pathology, Surgery and Emergency Medicine) and by leveraging our engineering innovations in microfluidics, single molecule spectroscopy and functional nanoparticles, we are developing genetic and epigenetic biomarker-based diagnostics , prognostics and monitoring for cancer and an array of other diseases.

Latest News:

06/2021 Dr. Wang is featured in the Summer 2021 issue of JHU Engineering magazine for developing microfluidic technologies to make the world healthier. Read the feature article here. Congratulations, Dr. Wang!

06/2021 Our lab will present 1 poster at Biosensors 2021. Looking forward to the excellent presentation!

06/2021 Our lab will present 1 talk and 1 poster at Global Health Workshop 2021 sponsored by the Chemical and Biological Microsystems Society (CBMS). Looking forward to excellent presentations! 

05/2021 Our lab will present 3 talks and 2 posters at Transducers 2021. Looking forward to excellent presentations!

05/2021 Dr. Chrissy O’Keefe won the Johns Hopkins Homewood Postdoc Association’s Elevator Pitch Competition. Congratulations!

05/2021 Dr. Hoan Ngo has joined our lab as a postdoctoral researcher. Dr. Ngo received his Ph.D. from Duke University and will work on translational point-of-care diagnostics for infectious diseases in the lab. Welcome!

05/2021 Johns Hopkins develops a portable device for rapidly diagnosing STIs. Our lab has created an inexpensive portable device and cellphone APP to diagnose gonorrhea in less than 15 minutes and determine if a particular strain will respond to frontline antibiotics. Results appear in today’s Science Translational Medicine.

03/2021  Alex Trick won the Whiting School of Engineering Trainee Research Award at the 2021 DOM/WSE Research Retreat for his work on a point-of-care magnetofluidic nucleic acid testing platform. 

01/2021 Our digital CRISPR-based detection of SARS-CoV-2, published in Advanced Science, is highlighted by Advanced Science News.

9/2020 Ph.D. student, Fangchi Shao won the C.M. Ho Best Paper Award at the Virtual IEEE-NEMS 2020 conference. The award-winning paper is entitled “A Programmable Nanodroplet Device with Direct Sample-to-Droplet Interface toward High-Throughput Screening”. Congratulations!

9/2020 Jeff Wang and Colleagues Receive Award to Develop HIV Self-Testing Technology. Jeff Wang and a multi-disciplinary team of researchers were awarded $3 million by the National Institutes of Health to develop a diagnostic device for self-testing HIV viral load.