{"id":2,"date":"2016-05-02T03:55:01","date_gmt":"2016-05-02T03:55:01","guid":{"rendered":"http:\/\/localhost\/biomems\/?page_id=2"},"modified":"2025-10-07T11:18:39","modified_gmt":"2025-10-07T15:18:39","slug":"sample-page","status":"publish","type":"page","link":"https:\/\/me.jhu.edu\/thwang\/","title":{"rendered":"Homepage"},"content":{"rendered":"\n<div class=\"text-center\">\n<h3>Translating Micro\/Nano Engineering Innovations into Clinic<\/h3>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Our lab focuses on the development of new technologies for molecular analysis and biomedical research via advances in micro-and nano-scale sciences. We aim to develop new methods, devices, and systems with unprecedented performance characteristics, such as sensitivity, specificity, resolution (temporal and\/or spatial), multiplexing, and throughput to rectify current technological limitations in the molecular study of diseases. By forging long-term collaborations with medical scientists and physicians across various disciplines (e.g. Oncology, Pathology, Surgery, and Emergency Medicine) and by leveraging our engineering innovations in microfluidics, single-molecule spectroscopy, and functional nanoparticles, we are developing genetic and epigenetic biomarker-based diagnostics, prognostics, and monitoring for cancer and an array of other diseases.<\/p>\n\n\n\n<h4 class=\"wp-block-heading color3\">Latest News:<\/h4>\n\n\n\n\n\n<div id=\"press-table\">\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2025\/10\/Freezer-Challenge-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" \/>09\/2025 We claimed Johns Hopkins\u2019 <em data-start=\"864\" data-end=\"890\">Top Performing Large Lab<\/em> honor in the <strong><a href=\"https:\/\/hub.jhu.edu\/2025\/09\/30\/johns-hopkins-earns-top-honors-in-annual-international-freezer-challenge\/\">2025 International Freezer Challenge<\/a><\/strong> by leading the charge toward greener, energy-smart research.<\/p>\n<p><span style=\"color: initial; font-size: revert;\"><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2024\/03\/Capture-300x136.jpg\" alt=\"\" width=\"169\" height=\"89\" \/>03\/2024 Our new antibiotic combination screening platform &#8211; RoboDrop &#8211; shows promises to identify potent combinations to improve treatments and safeguard the existing antibiotics. <a href=\"https:\/\/engineering.jhu.edu\/news\/meet-robodrop-the-superbug-slayer\/\"><strong>Meet RoboDrop, the Superbug Slayer<\/strong><\/a>.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2023\/09\/JHU-Siebel-Class-2024-JB1_0702_3000.jpg\" alt=\"\" width=\"169\" height=\"112\" \/>09\/2023 Fan-En Chen and Sixuan Li have been named <a href=\"https:\/\/hub.jhu.edu\/2023\/09\/25\/siebel-scholars-2024\/?utm_source=Hub+-+Synced+List&amp;utm_campaign=c5d6f4ced8-EMAIL_CAMPAIGN_2023_09_26_04_20&amp;utm_medium=email&amp;utm_term=0_3aa22d10c7-c5d6f4ced8-%5BLIST_EMAIL_ID%5D&amp;mc_cid=c5d6f4ced8&amp;mc_eid=0f8ad3d070\"><strong>2024 Siebel Scholars<\/strong><\/a>. Big congratulations!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2023\/04\/Picture1.jpg\" alt=\"\" width=\"167\" height=\"94\" \/><span style=\"font-size: revert; color: initial;\">04\/2023 Our <\/span><strong><a style=\"font-size: revert;\" href=\"https:\/\/www.nature.com\/articles\/s41467-022-33157-4\">paper<\/a><\/strong><span style=\"font-size: revert; color: initial;\"> on single-particle characterization of payload distribution and capacity of mRNA lipid nanoparticles is among the <\/span><a style=\"font-size: revert;\" href=\"https:\/\/www.nature.com\/collections\/dgiidcjfdh\"><strong>Top 25 Life and Biological Sciences Articles of 2022<\/strong><\/a><span style=\"font-size: revert; color: initial;\"> of Nature Communications.<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/pbs.twimg.com\/media\/Fn-YYXSWIAY8l5w?format=jpg&amp;name=large\" alt=\"Image\" width=\"95\" height=\"87\" \/>02\/2023 Dr. Li and Dr. Hsieh et al. have recently published an informative review paper <strong><a href=\"https:\/\/www.nature.com\/articles\/s43586-022-00190-y\">&#8220;Single-cell pathogen diagnostics for combating antibiotic resistance&#8221;<\/a><\/strong> on Nature Reviews Methods Primers.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2020\/09\/WangWeb-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>01\/2023 <span class=\"css-901oao css-16my406 r-poiln3 r-bcqeeo r-qvutc0\">Congratulations to Dr. Wang and 9 outstanding Hopkins faculty members for being elected <strong><a href=\"https:\/\/hub.jhu.edu\/2023\/01\/31\/ten-from-johns-hopkins-named-aaas-fellows\/\">American Association for the Advancement of Science (AAAS) <\/a><\/strong><\/span><span style=\"font-size: revert; color: initial;\">Fellows!<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2022\/09\/Nature-Communications-2-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>09\/2022 <a href=\"https:\/\/hub.jhu.edu\/2022\/09\/23\/cics-platform-for-measuring-genetic-medicine-in-lipid-nanoparticles\/\"><strong>Molecular Detection Platform Provides New Insights into Gene Medicine Manufacturing<\/strong><\/a> (from JHU HUB). Our collaborative work with Prof. Hai-Quan Mao\u2019s Lab on single-molecule spectroscopy characterizing the payload distribution and capacity of mRNA lipid nanoparticles was published in <a href=\"https:\/\/www.nature.com\/articles\/s41467-022-33157-4\"><strong>Nature Communications<\/strong><\/a>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2017\/09\/Hui-2021-1-150x150.jpg\" alt=\"\" width=\"96\" height=\"96\" \/>08\/2022 Dr. Hui Li accepted the Assistant Professor position in the School of Electrical, Computer, and Biomedical Engineering at Southern Illinois University. Congratulations!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/09\/NIH.png\" alt=\"\" width=\"95\" height=\"95\" \/>08\/2022 Our team led by Dr. Wang and Dr. Pisanic has been awarded a 3-year, $1.5M IMAT R33 grant from the National Cancer Institute to develop a simple and inexpensive blood test that can reliably detect and identify many types of cancers at early stages.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2020\/09\/WangWeb-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>09\/2021 Dr. Wang has been named the <a href=\"https:\/\/engineering.jhu.edu\/news\/tza-huei-jeff-wang-named-the-louis-m-sardella-professor\/\"><strong>Louis M. Sardella Professor<\/strong><\/a> in the Whiting School of Engineering. Congrats to Dr. Wang.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/09\/Circulomics-150x150.png\" alt=\"\" width=\"95\" height=\"95\" \/>08\/2021 08\/2021 We are extremely excited and proud that our lab spinoff, <a href=\"https:\/\/www.circulomics.com\/\"><strong>Circulomics<\/strong><\/a>, founded by our lab alum Dr. Kelvin Liu, was acquired by <a href=\"https:\/\/www.yahoo.com\/now\/pacific-biosciences-acquires-circulomics-leading-120000457.html\"><strong>Pacific Biosciences<\/strong><\/a>. Congrats to Kelvin and his team.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/09\/NIH.png\" alt=\"\" width=\"95\" height=\"95\" \/>08\/2021 Our team led by Dr. Wang and Dr. Pisanic has been awarded a 5-year, $2.2M R01 grant from the National Cancer Institute to develop a low-cost epigenetic screening assay for early-stage ovarian cancer!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2017\/09\/Wen2021-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>08\/2021 Dr. Kuangwen Hsieh is now an assistant research professor in the Department of Mechanical Engineering! Great achievement! Congrats!\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/08\/microTAS-2021-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>07\/2021 Our lab will present 5 posters and 1 oral at <strong><a href=\"https:\/\/microtas2021.org\/\">MicroTAS 2021<\/a><\/strong>. Good job, team! Looking forward to excellent presentations.\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2020\/09\/WangWeb-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>06\/2021 Dr. Wang is featured in the Summer 2021 issue of JHU Engineering magazine for developing microfluidic technologies to make the world healthier. Read the <strong><a href=\"https:\/\/engineering.jhu.edu\/magazine\/2021\/06\/getting-the-drop-on-better-health\/#.YMo6eqhKh3g\">feature article<\/a><\/strong> here. Congratulations, Dr. Wang!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/06\/Screen-Shot-2021-06-21-at-2.39.11-PM-150x150.png\" alt=\"\" width=\"95\" height=\"95\" \/>06\/2021 Our lab will present 1 poster at <a class=\"c-link\" href=\"https:\/\/www.elsevier.com\/events\/conferences\/world-congress-on-biosensors\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/www.elsevier.com\/events\/conferences\/world-congress-on-biosensors\" data-sk=\"tooltip_parent\"><strong>Biosensors 2021<\/strong><\/a>. Looking forward to the excellent presentation!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/06\/Screen-Shot-2021-06-21-at-2.45.38-PM-150x150.png\" alt=\"\" width=\"95\" height=\"95\" \/>06\/2021 Our lab will present 1 talk and 1 poster at<strong> <a class=\"c-link\" href=\"https:\/\/globalhealthworkshop.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/globalhealthworkshop.org\/\" data-sk=\"tooltip_parent\">Global Health Workshop 2021<\/a> <\/strong>sponsored by the Chemical and Biological Microsystems Society (CBMS). Looking forward to excellent presentations!<span class=\"c-message__edited_label\" dir=\"ltr\" data-sk=\"tooltip_parent\">\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/06\/logo-transducers2021-150x150.png\" alt=\"\" width=\"95\" height=\"95\" \/>05\/2021 Our lab will present 3 talks and 2 posters at <a class=\"c-link\" href=\"https:\/\/transducers2021.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/transducers2021.org\/\" data-sk=\"tooltip_parent\"><strong>Transducers 2021<\/strong><\/a>. Looking forward to excellent presentations!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2016\/05\/xsy-150x150.jpg\" alt=\"\" width=\"95\" height=\"95\" \/>05\/2021 Dr. Chrissy O&#8217;Keefe won the Johns Hopkins Homewood Postdoc Association&#8217;s Elevator Pitch Competition. Congratulations!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2017\/09\/Hoan-photo-150x150.png\" alt=\"\" width=\"95\" height=\"95\" \/>05\/2021 Dr. Hoan Ngo has joined our lab as a postdoctoral researcher. Dr. Ngo received his Ph.D. from Duke University and will work on translational point-of-care diagnostics for infectious diseases in the lab. Welcome!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/05\/Alex-Rapid-STI-diagnosis-150x150.jpg\" alt=\"\" width=\"90\" height=\"90\" \/>05\/2021 <a href=\"https:\/\/me.jhu.edu\/2021\/05\/14\/johns-hopkins-develops-portable-device-for-rapidly-diagnosing-stis\/#.YJ6GZqhKg2x\"><strong>Johns Hopkins develops a portable device for rapidly diagnosing STIs<\/strong>.<\/a> Our lab has created an inexpensive portable device and cellphone APP to diagnose gonorrhea in less than 15 minutes and determine if a particular strain will respond to frontline antibiotics. Results appear in today\u2019s <a href=\"https:\/\/stm.sciencemag.org\/content\/13\/593\/eabf6356\"><strong>Science Translational Medicine<\/strong><\/a>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2016\/05\/Trixie.jpg\" alt=\"\" width=\"90\" height=\"90\" \/>03\/2021 \u00a0Alex Trick won the Whiting School of Engineering Trainee Research Award at the 2021 DOM\/WSE Research Retreat for his work on a point-of-care magnetofluidic nucleic acid testing platform.\u00a0<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left alignnone\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2021\/01\/FigureTOC.png\" width=\"90\" height=\"81\" \/>01\/2021 <a href=\"https:\/\/www.advancedsciencenews.com\/digital-crispr%E2%80%90assisted-assay-for-rapid-detection-of-sars%E2%80%90cov%E2%80%902\/\"><b>Our digital CRISPR-based detection of SARS-CoV-2, published in Advanced Science, is highlighted by Advanced Science News<\/b>.<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left\" src=\"https:\/\/me.jhu.edu\/thwang\/\/images\/2020\/09\/Fangchi_Shao_Portrait-150x150.jpg\" alt=\"\" width=\"85\" height=\"85\" \/>9\/2020 <b>Ph.D. student, Fangchi Shao won the C.M. Ho Best Paper Award at the Virtual IEEE-NEMS 2020 conference. <\/b>The award-winning paper is entitled \u201cA Programmable Nanodroplet Device with Direct Sample-to-Droplet Interface toward High-Throughput Screening&#8221;. Congratulations!<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"float-left\" src=\"images\/News\/Dr.wang.jpg\" width=\"100\" height=\"70\" \/>9\/2020 <a href=\"https:\/\/inbt.jhu.edu\/jeff-wang-and-colleagues-receive-award-to-develop-hiv-self-testing-technology\/\"><b>Jeff Wang and Colleagues Receive Award to Develop HIV Self-Testing Technology. <\/b><\/a>Jeff Wang and a multi-disciplinary team of researchers were awarded $3 million by the National Institutes of Health to develop a diagnostic device for self-testing HIV viral load.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-horizontal is-content-justification-right is-layout-flex wp-container-core-buttons-is-layout-80f27767 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-50 is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-white-color has-text-color wp-element-button\" href=\"https:\/\/twitter.com\/JHUBioMEMS\"><span style=\"background-color:#ffffff\" class=\"tadv-background-color\"><span style=\"color:#000000\" class=\"tadv-color\"><strong>Check out our group Twitter by clicking here<\/strong><\/span><\/span><\/a><\/div>\n<\/div>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>Translating Micro\/Nano Engineering Innovations into Clinic Our lab focuses on the development of new technologies for molecular analysis and biomedical research via advances in micro-and nano-scale sciences. We aim to develop new methods, devices, and systems with unprecedented performance characteristics, such as sensitivity, specificity, resolution (temporal and\/or spatial), multiplexing, and throughput to rectify current technological [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-2","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/pages\/2","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/comments?post=2"}],"version-history":[{"count":222,"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/pages\/2\/revisions"}],"predecessor-version":[{"id":2063,"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/pages\/2\/revisions\/2063"}],"wp:attachment":[{"href":"https:\/\/me.jhu.edu\/thwang\/wp-json\/wp\/v2\/media?parent=2"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}