Department of Mechanical Engineering 2018 Fall Seminar Series
Micro Mechanical Methods for Biology (M3B)
Presented by Professor Liwei Lin
University of California, Berkeley
Next-generation autonomous microfluidic components, circuits and systems have been widely investigated for the past decades by researchers from various disciplines, including mechanical engineering, electrical engineering, bioengineering, chemistry and biology. They key focuses have been making microfluidic systems with functions similar to microelectronics with possible applications related to biological/medical problems. This talk will start with the discussions on the background information on the development of microfluidic components and systems. It will then followed with specific progresses from my laboratory in relevant topics, including: (1) the application of optofluidic lithography in the making and demonstration of microfluidic diodes with three different versions: bead-based operations, swing check valves, and spring check valves; (2) micro mechanical platforms for cell mechanobiology to control the cellular functions with two approaches: bi-axial control of substrate stiffness using micropost arrays of varying diameter, and tri-axial stiffness control using microscale springs; and (3) microfluidics based on the 3D printing techniques.
Professor Liwei Lin received PhD degree from the University of California, Berkeley, in 1993. He was an Associate Professor in the Institute of Applied Mechanics, National Taiwan University, Taiwan (1994~1996) and an Assistant Professor in Mechanical Engineering Department, University of Michigan (1996~1999). He joined the University of California at Berkeley in 1999 and is now James Marshall Wells Professor at the Mechanical Engineering Department and Co-Director at Berkeley Sensor and Actuator Center (BSAC), an NSF/Industry/University research cooperative center. His research interests are in design, modeling and fabrication of micro/nano structures, sensors and actuators as well as mechanical issues in micro/nano systems including heat transfer, solid/fluid mechanics and dynamics. Dr. Lin is the recipient of the 1998 NSF CAREER Award for research in MEMS Packaging and the 1999 ASME Journal of Heat Transfer best paper award for his work on micro scale bubble formation. He led the effort to establish the MEMS division in ASME and served as the founding Chairman of the Executive Committee from 2004~2005. He is an ASME Fellow and has 20 issued US patents in the area of MEMS. He was the general co-chair of the 24th international conference on Micro Electro Mechanical Systems at Cancun, Mexico. Currently, he serves as a subject editor for the IEEE/ASME Journal of Microelectromechanical Systems and the North and South America Editor of Sensors and Actuators –A Physical.